The immune informatics group manages assay data and computing resources for collaborative CHSI projects. Our team also develops reproducible pipelines for standard and novel assays used by investigators.
- Management of assay data. The immune informatics group is responsible for managing the storage, annotation, and curation of immunological data sets for CHSI collaborative projects. In addition to data, metadata that meet minimal standards requirements for uploading to public repositories is maintained.
- Development of reproducible pipelines. The immune informatics group develops containerized pipelines for scalable and reproducible analysis. Pipelines are currently being developed for flow cytometry, bulk RNA-seq, scRNA-seq, TCR and BCR repertoires, and immuno-histochemistry/immunofluorescent (IHC/IF) image analysis. Custom pipelines for novel assays can also be developed collaboratively with investigators.
- Computing resources. Our computing resources consist of 20 servers (each with 4 GPUs, 44 CPU cores, and 384/768 GB RAM) on the Duke Compute Cluster. Immunology researchers with large computing needs are encouraged to consult the group or participate in the quarterly RFP for computationally intensive immunology projects. There is no charge to use the computing resources or bioinformatics expertise for projects selected in the quarterly RFP.