Dr. Sekaran leads the Biophysical Immunology group engaged in studying the dynamics of vaccine elicited antibodies-antigen interactions aimed to accelerate progress in combating and eradicating diseases of global health importance.  We use Biolayer Interferometry (BLI) and Surface Plasmon Resonance imaging (SPRi) techniques to address questions related to epitope recognition by monoclonal and polyclonal antibodies that are protective against infection by pathogens.